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Muralidhar Beeram Selected Research

Ado-Trastuzumab Emtansine

12/2012A phase 1 study of weekly dosing of trastuzumab emtansine (T-DM1) in patients with advanced human epidermal growth factor 2-positive breast cancer.
5/2012Clinical implications of pathophysiological and demographic covariates on the population pharmacokinetics of trastuzumab emtansine, a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer.
6/2010Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancer.

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Muralidhar Beeram Research Topics

Disease

26Neoplasms (Cancer)
12/2022 - 10/2002
7Breast Neoplasms (Breast Cancer)
01/2021 - 06/2010
5Exanthema (Rash)
01/2018 - 12/2006
4Fatigue
01/2019 - 06/2010
4Neutropenia
02/2017 - 01/2007
4Melanoma (Melanoma, Malignant)
01/2016 - 02/2007
2Stomatitis
01/2018 - 02/2017
2Mucositis
02/2017 - 04/2012
2Fever (Fevers)
06/2007 - 01/2007
1Bone Diseases (Bone Disease)
01/2021
1Cholangiocarcinoma
01/2019
1Tremor (Tremors)
01/2018
1Dermatitis
01/2018
1Paronychia
01/2018
1Hypokalemia
01/2018
1Hepatocellular Carcinoma (Hepatoma)
03/2016
1Glioblastoma (Glioblastoma Multiforme)
01/2016
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016
1Infections
10/2015
1Gastritis
10/2015
1Pericarditis
10/2014
1Obesity
08/2014
1Overweight
08/2014
1Inflammation (Inflammations)
08/2014
1Pruritus (Itching)
08/2014
1Proteinuria
05/2014
1Febrile Neutropenia
06/2013
1Body Weight (Weight, Body)
05/2012
1Thrombocytopenia (Thrombopenia)
06/2010
1Anemia
06/2010
1Nausea
06/2010

Drug/Important Bio-Agent (IBA)

3Hormones (Hormone)IBA
01/2021 - 01/2016
3Aromatase InhibitorsIBA
01/2021 - 08/2014
3Proteins (Proteins, Gene)FDA Link
01/2018 - 10/2002
3Monoclonal AntibodiesIBA
03/2016 - 05/2014
3Sorafenib (BAY 43-9006)FDA Link
07/2014 - 09/2005
3Ado-Trastuzumab EmtansineIBA
12/2012 - 06/2010
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2021 - 01/2016
2TamoxifenFDA LinkGeneric
01/2021 - 03/2016
2abemaciclibIBA
01/2021 - 01/2016
2p38 Mitogen-Activated Protein KinasesIBA
01/2018 - 03/2016
2vesencumabIBA
08/2014 - 05/2014
2Bevacizumab (Avastin)FDA Link
07/2014 - 05/2014
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2014 - 02/2007
2Paclitaxel (Taxol)FDA LinkGeneric
05/2014 - 12/2006
2Immunoconjugates (Immunoconjugate)IBA
05/2012 - 06/2010
2Transaminases (Aminotransferases)IBA
04/2012 - 06/2010
2Pemetrexed (MTA)FDA Link
05/2007 - 01/2007
1zanidatamabIBA
12/2022
1Letrozole (Femara)FDA LinkGeneric
01/2021
1exemestane (Aromasin)FDA Link
01/2021
1Fulvestrant (Faslodex)FDA Link
01/2021
1Anastrozole (Arimidex)FDA LinkGeneric
01/2021
1Phosphorus (Red Phosphorus)IBA
01/2019
1magrolimabIBA
01/2019
1Alkaline PhosphataseIBA
01/2019
1isocitric acid (isocitrate)IBA
01/2019
1ivosidenibIBA
01/2019
1ErbB Receptors (EGF Receptor)IBA
01/2018
1Creatine Kinase (Creatine Phosphokinase)IBA
01/2018
1pegfilgrastim (Neulasta)FDA Link
02/2017
1litronesibIBA
02/2017
1Biomarkers (Surrogate Marker)IBA
03/2016
1Fetal Proteins (Fetoprotein)IBA
03/2016
1CytokinesIBA
03/2016
1ralimetinibIBA
03/2016
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2015
1pembrolizumabIBA
10/2015
17- (4- (3- ethynylphenylamino)- 7- methoxyquinazolin- 6- yloxy)- N- hydroxyheptanamideIBA
10/2014
1CreatinineIBA
10/2014
1Aromatase (CYP19)IBA
08/2014
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
08/2014
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2014
1Estrogens (Estrogen)FDA Link
08/2014
1EnzymesIBA
08/2014
1ProstaglandinsIBA
08/2014
1EicosanoidsIBA
08/2014
1Estrogen ReceptorsIBA
08/2014
1Dinoprostone (PGE2)FDA Link
08/2014
1Dexamethasone (Maxidex)FDA LinkGeneric
08/2014
1Ethylene Glycol (Monoethylene Glycol)IBA
06/2013
1EZN-2208IBA
06/2013
1Epidermal Growth Factor (EGF)IBA
12/2012
1Trastuzumab (Herceptin)FDA Link
12/2012
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
05/2012
1AlbuminsIBA
05/2012
1Phosphatidylinositols (Phosphatidylinositol)IBA
04/2012
1Mitogen-Activated Protein KinasesIBA
04/2012
1Cisplatin (Platino)FDA LinkGeneric
12/2009
1troxacitabineIBA
12/2009
1XRP6258IBA
01/2009
1taxaneIBA
01/2009
1Dacarbazine (DIC)FDA LinkGeneric
05/2008
1AI-850IBA
06/2007

Therapy/Procedure

6Therapeutics
12/2022 - 10/2002
3Drug Therapy (Chemotherapy)
01/2021 - 05/2008
1Duration of Therapy
03/2016
1Radiotherapy
03/2016
1Premedication
08/2014